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Clin Infect Dis. 2013 Nov;57(9):1300-3. doi: 10.1093/cid/cit453. Epub 2013 Jul 9.

Higher incidence of acute kidney injury with intravenous colistimethate sodium compared with polymyxin B in critically ill patients at a tertiary care medical center.

Author information

1
Department of Pharmacy Practice, D'Youville College School of Pharmacy, Buffalo.

Abstract

Nephrotoxicity was assessed in 173 critically ill patients receiving intravenous colistin or polymyxin B; it occurred in 60.4% and 41.8%, respectively. Further investigation is necessary to elucidate the reason for the difference in nephrotoxicity observed between the groups and to assess the impact of severity of illness and dosing/administration.

KEYWORDS:

AKI; PB; colistimethate sodium; colistin; nephrotoxicity

PMID:
23840000
DOI:
10.1093/cid/cit453
[Indexed for MEDLINE]

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