LDK378: a promising anaplastic lymphoma kinase (ALK) inhibitor

J Med Chem. 2013 Jul 25;56(14):5673-4. doi: 10.1021/jm401005u. Epub 2013 Jul 9.
No abstract available

Publication types

  • Comment

MeSH terms

  • Anaplastic Lymphoma Kinase
  • Animals
  • Humans
  • Male
  • Neoplasms / drug therapy*
  • Protein Kinase Inhibitors / chemical synthesis*
  • Pyrimidines / chemical synthesis*
  • Receptor Protein-Tyrosine Kinases / antagonists & inhibitors*
  • Sulfones / chemical synthesis*

Substances

  • Protein Kinase Inhibitors
  • Pyrimidines
  • Sulfones
  • ALK protein, human
  • Anaplastic Lymphoma Kinase
  • Receptor Protein-Tyrosine Kinases
  • ceritinib