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Hum Vaccin Immunother. 2013 Jun;9(6):1289-91. doi: 10.4161/hv.24182. Epub 2013 Mar 6.

A reverse evidence of rotavirus vaccines impact.

Author information

1
Área Asistencial Integrada de Pediatría; Hospital Clínico Universitario de Santiago de Compostela; Santiago de Compostela, Spain; Red Gallega de Investigación Pediátrica; Santiago de Compostela, Spain; Grupo de investigación en Genética, Vacunas, Infecciones y Pediatria (GENVIP-www.genvip.org); Instituto de Investigación Sanitaria de Santiago (IDIS); Santiago de Compostela, Spain.

Abstract

In 2010, and due to a quality problem identified in the vaccine manufacture, the rotavirus (RV) vaccination was withheld in Spain during 5 months. Our study aimed to evaluate the impact that this sudden cease had on rotavirus acute gastroenteritis (RAGE) hospitalizations. An increase in RAGE hospitalization was observed in parallel to the drop in vaccine coverage. Here, we report the first reverse evidence of rotavirus vaccine impact.

KEYWORDS:

Vaccine effectiveness; gastroenteritis/epidemiology; hospitalization; rotavirus infections/prevention & control; rotavirus vaccines

PMID:
23836258
PMCID:
PMC3901818
DOI:
10.4161/hv.24182
[Indexed for MEDLINE]
Free PMC Article

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