[Renal cell carcinoma producing erythrocytosis due to inappropriate production of erythropoietin]

Semergen. 2013 Jul-Aug;39(5):282-4. doi: 10.1016/j.semerg.2012.04.013. Epub 2012 Jun 15.
[Article in Spanish]

Abstract

Erythrocytosis, or polycythaemia, is an increase, in absolute terms, of the erythrocyte mass. The most common solid tumour related to this phenomenon is renal cell carcinoma, which can produce erythrocytosis by increasing erythropoietin production. About 30% of symptomatic renal cell carcinomas are diagnosed due to the appearance of a paraneoplastic syndrome. Polycythaemia is one of these. Surgery, (radical or partial nephrectomy), is the treatment of choice in renal cell carcinoma and helps to keep the erythrocytosis situation under control.

Keywords: Carcinoma renal de células claras; Eritrocitosis; Erythrocytosis; Paraneoplastic syndrome; Poliglobulia; Polycythaemia; Renal cell carcinoma; Síndrome paraneoplásico.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Carcinoma, Renal Cell / complications*
  • Carcinoma, Renal Cell / metabolism*
  • Erythropoietin / biosynthesis*
  • Female
  • Humans
  • Kidney Neoplasms / complications*
  • Kidney Neoplasms / metabolism*
  • Middle Aged
  • Polycythemia / etiology*

Substances

  • Erythropoietin