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Org Lett. 2013 Jul 5;15(13):3222-5. doi: 10.1021/ol401139m. Epub 2013 Jun 19.

A new strategy for the construction of α-amino acid esters via decarboxylation.

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1
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China.

Abstract

A new α-amino acid esters formation reaction has been developed via decarboxylation. The methodology is distinguished by its practical novelty in terms of the readily accessible starting materials, environmentally benign reaction conditions and waste streams, and wide substrate scope.

PMID:
23826673
DOI:
10.1021/ol401139m
[Indexed for MEDLINE]
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