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J Thorac Dis. 2013 Jun;5(3):326-34. doi: 10.3978/j.issn.2072-1439.2013.04.05.

Acute respiratory distress syndrome: new definition, current and future therapeutic options.

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1
Department of Anesthesia and Critical Care Medicine, University of Turin, Azienda Ospedaliera Città della Salute e della Scienza di Torino, Italy;

Abstract

Since acute respiratory distress syndrome (ARDS) was first described in 1967 there has been large number of studies addressing its pathogenesis and therapies. Despite this intense research activity, there are very few effective therapies for ARDS other than the use of lung protection strategies. This lack of therapeutic modalities is not only related to the complex pathogenesis of this syndrome but also the insensitive and nonspecific diagnostic criteria to diagnose ARDS. This review article will summarize the key features of the new definition of ARDS, and provide a brief overview of innovative therapeutic options that are being assessed in the management of ARDS.

KEYWORDS:

Acute respiratory distress syndrome (ARDS); pathogenesis; therapeutic options

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