Format

Send to

Choose Destination
See comment in PubMed Commons below
Proc Biol Sci. 2013 Jul 3;280(1765):20130011. doi: 10.1098/rspb.2013.0011. Print 2013 Aug 22.

Adaptation of molecular circadian clockwork to environmental changes: a role for alternative splicing and miRNAs.

Author information

1
Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat-Ram, 91904 Jerusalem, Israel.

Abstract

Circadian (24 h) clocks provide a source of internal timing in most living organisms. These clocks keep time by using complex transcriptional/post-translational feedback loops that are strikingly resilient to changes in environmental conditions. In the last few years, interest has increased in the role of post-transcriptional regulation of circadian clock components. Post-transcriptional control plays a prominent role in modulating rapid responses of the circadian system to environmental changes, including light, temperature and general stress and will be the focus of this review.

KEYWORDS:

circadian clock; environment; post-transcriptional regulation

PMID:
23825200
PMCID:
PMC3712432
DOI:
10.1098/rspb.2013.0011
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center