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J Clin Microbiol. 2013 Sep;51(9):3102-6. doi: 10.1128/JCM.00351-13. Epub 2013 Jul 3.

Evaluation of a new commercially available immunoglobulin M capture enzyme-linked immunosorbent assay for diagnosis of dengue virus infection.

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1
Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.

Abstract

We evaluated the FDA-cleared InBios dengue virus (DENV) IgM capture enzyme-linked immunosorbent assay (ELISA) for qualitative detection of anti-DENV IgM antibodies from 79 serum samples obtained from dengue virus-infected patients or suspected dengue cases. The agreement, sensitivity, and specificity of the InBios assay compared to the gold standard in-house DENV IgM capture ELISA were 94, 92, and 94%, respectively. We conclude that the InBios DENV IgM capture ELISA can be effectively used for rapid diagnosis of acute or recent DENV infection.

PMID:
23824771
PMCID:
PMC3754626
DOI:
10.1128/JCM.00351-13
[Indexed for MEDLINE]
Free PMC Article
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