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Molecules. 2013 Jul 3;18(7):7751-60. doi: 10.3390/molecules18077751.

Two new phenolic glycosides from Gnaphalium affine D. Don and their anti-complementary activity.

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1
School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, China.

Abstract

Two new phenolic glycosides, named gnaphaffine A and B (compounds 1 and 2), were isolated from Gnaphalium affine. together with six known compounds, including caffeic acid (3), everlastoside L (4), isorhamnetin-7-O-β-D-glucopyranoside (5), quercetin- 3-O-β-D-glucopyranoside (6), scutellarein-7-O-β-D-glucoside (7) and api-genin-7-O-β-D- glucopyranoside (8). Their structures were elucidated by spectroscopic methods, including ESI-MS and 2D NMR spectroscopy (HMQC and HMBC). All compounds were evaluated for their anti-complementary activity on the classical pathway of the complement system in vitro.

PMID:
23823875
DOI:
10.3390/molecules18077751
[Indexed for MEDLINE]
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