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Leukemia. 2014 Jan;28(1):198-201. doi: 10.1038/leu.2013.204. Epub 2013 Jul 4.

Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies.

Author information

1
Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
2
1] Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA [2] Department of Chemistry and Molecular Biosciences, Chemistry of Life Processes, Northwestern University, Evanston, IL, USA.
3
Department of Chemistry and Molecular Biosciences, Chemistry of Life Processes, Northwestern University, Evanston, IL, USA.
4
University of Maryland School of Pharmacy, University of Maryland Greenebaum Cancer Center, Baltimore, MD, USA.
5
Department of Pathology, Department of Pediatrics, Institute for Cancer Genetics, Columbia University, New York, NY, USA.
6
Human Oncology and Pathogenesis Program, Leukemia Service, Department of medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
7
Deparment of Medicine, Division of Hematology/oncology, Department of Pharmacology, Weill Cornell Medical College, New York, NY, USA.
PMID:
23823660
PMCID:
PMC3888226
DOI:
10.1038/leu.2013.204
[Indexed for MEDLINE]
Free PMC Article
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