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Structure. 2013 Jul 2;21(7):1068-70. doi: 10.1016/j.str.2013.06.009.

Decoding a chain letter for degradation.

Author information

1
Department of Early Discovery Biochemistry, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

Abstract

Ubiquitin chains can have distinct signaling outcomes, depending on their conjugation point. In this issue of Structure, CastaƱeda and colleagues describe a new structure of K11 diubiquitin and investigate its recognition by effectors to target substrates to the proteasome.

PMID:
23823323
DOI:
10.1016/j.str.2013.06.009
[Indexed for MEDLINE]
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