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Biophys J. 2013 Jul 2;105(1):3-10. doi: 10.1016/j.bpj.2013.05.039.

Physical models of mesoderm invagination in Drosophila embryo.

Author information

1
European Molecular Biology Laboratory Heidelberg, Heidelberg, Germany.

Abstract

The invagination of the mesoderm in the Drosophila melanogaster embryo is an intensely studied example of epithelial folding. Several theoretical studies have explored the conditions and mechanisms needed to reproduce the formation of the invagination in silico. Here we discuss the aspects of epithelial folding captured by these studies, and compare the questions addressed, the approaches used, and the answers provided.

PMID:
23823218
PMCID:
PMC3699736
DOI:
10.1016/j.bpj.2013.05.039
[Indexed for MEDLINE]
Free PMC Article

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