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Methods Mol Biol. 2013;1030:373-82. doi: 10.1007/978-1-62703-484-5_29.

In vivo evaluation of antiviral compounds on respiratory syncytial virus using a juvenile vervet monkey (Chlorocebus pygerythrus) infection model.

Author information

1
Rega Institute for Medical Research, University of Leuven, Leuven, Belgium.

Abstract

Several animal models with varying susceptibilities to respiratory syncytial virus (RSV) infection have been developed to study the specific aspects of RSV disease. Many of these models are used for testing antiviral compounds or in vaccine efficacy studies during preclinical evaluation. In this chapter, we describe the study design of an efficacy study of an RSV inhibitor, performed in a juvenile vervet monkey model for RSV.

PMID:
23821283
DOI:
10.1007/978-1-62703-484-5_29
[Indexed for MEDLINE]

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