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Methods Mol Biol. 2013;1030:205-19. doi: 10.1007/978-1-62703-484-5_17.

High-throughput screening using dengue virus reporter genomes.

Author information

1
Haplogen GmbH, Vienna, Austria.

Abstract

Large-scale antiviral drug discovery and systematic identification of host factors promoting or restricting virus replication require robust, scalable, and cost-effective assay systems that allow for high throughput and automation. Here we describe the construction and application of full-length infectious dengue virus reporter genomes for such screening applications.

PMID:
23821271
DOI:
10.1007/978-1-62703-484-5_17
[Indexed for MEDLINE]

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