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Physiology (Bethesda). 2013 Jul;28(4):245-53. doi: 10.1152/physiol.00010.2013.

Darkness at the end of the tunnel: poststenotic kidney injury.

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1
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.

Abstract

Renal artery stenosis remains an important contributor to renal failure in the elderly population, but uncertainty continues to surround the mechanisms underlying progressive renal dysfunction. Here, we present the current understanding of the pathogenic mechanisms responsible for renal injury in these patients, with emphasis on those involved in disease progression.

PMID:
23817799
PMCID:
PMC3742129
DOI:
10.1152/physiol.00010.2013
[Indexed for MEDLINE]
Free PMC Article
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