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Arch Dis Child. 2013 Oct;98(10):812-7. doi: 10.1136/archdischild-2013-304611. Epub 2013 Jun 27.

An overview of respiratory problems in children with Down's syndrome.

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PICU and Respiratory Medicine, Nottingham University Hospital, , Nottingham, UK.


Respiratory disease is a common cause of morbidity and mortality in children with Down's syndrome (DS). Causes range from those problems common to many children with DS, such as a narrow airway or impaired immunity, to rare structural lesions, such as tracheal bronchus. Additionally, other organ systems or extrinsic factors may play a role. A thorough understanding of the range of potential problems will aid in the evaluation and management of children with DS and respiratory symptoms.

[Indexed for MEDLINE]

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