Abstract
Short-chain fatty acids produced by anaerobic bacteria of the periodontal pockets inhibit lymphocytes activation. The highest degrees of immunosuppressive activity is produced by butyric acid.
MeSH terms
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Bacteria, Anaerobic / immunology*
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Bacteria, Anaerobic / metabolism
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Fatty Acids, Volatile / biosynthesis
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Fatty Acids, Volatile / immunology*
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Humans
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Immune Tolerance / drug effects
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Immune Tolerance / immunology*
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Immunity, Cellular / drug effects
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Immunity, Cellular / immunology
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Lymphocyte Activation / drug effects
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Lymphocyte Activation / immunology
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Monocytes / drug effects
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Monocytes / immunology
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Periodontal Pocket / immunology*
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Periodontal Pocket / microbiology
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Periodontitis / immunology*
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T-Lymphocytes / drug effects
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T-Lymphocytes / immunology