Format

Send to

Choose Destination
Science. 2013 Aug 16;341(6147):783-786. doi: 10.1126/science.1239022. Epub 2013 Jun 27.

Identification of wheat gene Sr35 that confers resistance to Ug99 stem rust race group.

Author information

1
Kansas State University, Dept. Plant Pathology, Manhattan, KS 66506.
2
University of California, Davis Dept. Plant Sciences, Davis, CA 95616.
3
USDA-ARS Cereal Disease Laboratory, St. Paul, MN 55108.
4
Howard Hughes Medical Institute, Chevy Chase, MD 20815.
#
Contributed equally

Abstract

Wheat stem rust, caused by Puccinia graminis f. sp. tritici (Pgt), is a devastating disease that can cause severe yield losses. A previously uncharacterized Pgt race, designated Ug99, has overcome most of the widely used resistance genes and is threatening major wheat production areas. Here, we demonstrate that the Sr35 gene from Triticum monococcum is a coiled-coil, nucleotide-binding, leucine-rich repeat gene that confers near immunity to Ug99 and related races. This gene is absent in the A-genome diploid donor and in polyploid wheat but is effective when transferred from T. monococcum to polyploid wheat. The cloning of Sr35 opens the door to the use of biotechnological approaches to control this devastating disease and to analyses of the molecular interactions that define the wheat-rust pathosystem.

PMID:
23811222
PMCID:
PMC4748951
DOI:
10.1126/science.1239022
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center