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J Glaucoma. 2015 Mar;24(3):207-13. doi: 10.1097/IJG.0b013e31829e1d84.

Coexistence and development of an open-angle glaucoma in eyes with superior segmental optic hypoplasia.

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*Department of Ophthalmology, Eulji Medical Center, Eulji University School of Medicine ∥Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea †Ozaki Eye Hospital ‡Department of Ophthalmology, Faculty of Medicine, University of Miyazaki §Department of Orthoptics and Visual Sciences, School of Health Sciences, Kyushu University of Health and Welfare, Miyazaki, Japan.



Superior segmental optic hypoplasia (SSOH) is a congenital disorder that is expected not to progress. This study aimed to determine the prevalence and clinical characteristics of coexistent open-angle glaucoma (OAG) in patients with SSOH.


We retrospectively reviewed the records of 61 patients diagnosed with SSOH. The estimated prevalence and clinical characteristics of concomitant OAG among patients with SSOH were investigated.


Of the 61 patients with SSOH, 12 patients presented with concomitant OAG (mean age, 44.8±19.2 y). Mean follow-up period was 84.9±50.9 months. Five patients (8.2%) were diagnosed with both high-tension glaucoma (HTG) and SSOH; 4 had HTG and SSOH in both the eyes; and the other had HTG only in the eye with SSOH. Seven patients (11.5%) were diagnosed with both normal-tension glaucoma (NTG) and SSOH. Two patients had NTG and SSOH in both eyes and 5 patients had unilateral NTG. The estimated prevalence of OAG in patients with SSOH was 19.7% (95% confidence interval, 9.7%-29.7%).


Primary OAG, including HTG and NTG, could develop in eyes with SSOH, regarded as having a nonprogressive visual field defect. The estimated prevalence of OAG, including both NTG and HTG, might be relatively higher in the SSOH patients. Thus, continuous follow-up examinations of patients with SSOH are required.

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