Format

Send to

Choose Destination
See comment in PubMed Commons below
World J Pediatr Congenit Heart Surg. 2011 Apr;2(2):316-7. doi: 10.1177/2150135110394217.

Delayed arterial switch operation for d-transposition of the great arteries and glucocorticoid remediable aldosteronism.

Author information

1
Division of Pediatric Cardiology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.

Abstract

The Jatene arterial switch operation (ASO) for dextro-transposition of the great arteries is ideally performed within the first 2 weeks of life. Clinical circumstances, however, may dictate a delayed ASO and left ventricle "retraining" prior to the procedure. Glucocorticoid remediable aldosteronism (GRA) accounts for 0.5% to 1% of primary aldosteronism. It presents as severe hypertension in infants and children, with poor response to standard antihypertensive medications. To the authors' knowledge, this is the first reported case of GRA in the context of transposition physiology. The management of GRA and a rationale for delayed ASO are discussed.

KEYWORDS:

arterial switch operation; comorbidity; congenital heart surgery; endocrinology; preconditioning

PMID:
23804991
DOI:
10.1177/2150135110394217
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center