The predisposition to thyrotoxic periodic paralysis (TPP) is due to a genetic variant in the inward-rectifying potassium channel, KCNJ2

Clin Endocrinol (Oxf). 2014 May;80(5):770-1. doi: 10.1111/cen.12277. Epub 2013 Jul 31.

Authors

Xingyan Wang¹, Chun Chung Chow, Xiaoqiang Yao, Gary T C Ko, Clive S Cockram, Hoi Kei Kwok, Jinglin Zhang, Nelson L S Tang

Affiliation

¹ Department of Chemical Pathology, The Chinese University of Hong Kong, N.T., Hong Kong SAR; Functional Genomics and Biostatistical Computing Laboratory, Shenzhen Research Institute of the Chinese University of Hong Kong.

PMID: 23803013
DOI: 10.1111/cen.12277

No abstract available

Publication types

Letter

MeSH terms

Adult
Case-Control Studies
China
Gene Frequency
Genetic Predisposition to Disease*
Genetic Variation*
Genotype
Graves Disease / genetics
Humans
Hypokalemic Periodic Paralysis / diagnosis*
Male
Middle Aged
Potassium Channels, Inwardly Rectifying / genetics*
Sequence Analysis, DNA
Temperature
Thailand

Substances

KCNJ2 protein, human
Potassium Channels, Inwardly Rectifying