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Ann Clin Biochem. 2013 Sep;50(Pt 5):492-5. doi: 10.1177/0004563213481207. Epub 2013 Jun 25.

Ailing bones and failing kidneys: a case of chronic cadmium toxicity.

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Department of Biochemistry, Peerless Hospital and BK Roy Research Center, Kolkata, India.


Heavy metal toxicity is often caused by occupational exposure. Chronic cadmium toxicity is a significant health concern among workers engaged in zinc smelting, battery production and silver jewellery industries, particularly in developing countries. We report the case of a 48-year-old man who presented with severe osteoporosis, impaired renal function and acquired Fanconi syndrome. He was finally diagnosed with chronic cadmium toxicity resulting from long-term occupational exposure. Cadmium has a long biological half-life and there is no effective treatment for people who are exposed to it. Therefore, an early diagnosis and prevention of further exposure are important.


Disease; bone disorders; toxicology

[Indexed for MEDLINE]

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