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BMC Biol. 2013 Jun 24;11:71. doi: 10.1186/1741-7007-11-71.

Mitochondrial network morphology: building an integrative, geometrical view.

Author information

1
Department of Developmental and Cell Biology and Center for Complex Biological Systems, University of California, Irvine, CA 92697, USA. susanner@uci.edu

Abstract

The morphology of mitochondrial networks is complex and highly varied, yet vital to cell function. The first step toward an integrative understanding of how mitochondrial morphology is generated and regulated is to define the interdependent geometrical features and their dynamics that together generate the morphology of a mitochondrial network within a cell. Distinct aspects of the size, shape, position, and dynamics of mitochondrial networks are described and examples of how these features depend on one another discussed.

PMID:
23800141
PMCID:
PMC3691739
DOI:
10.1186/1741-7007-11-71
[Indexed for MEDLINE]
Free PMC Article

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