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Br J Dermatol. 2013 Oct;169(4):848-53. doi: 10.1111/bjd.12482.

Clinical and dermoscopic characteristics of new naevi in adults: results from a cohort study.

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Department of Dermatology, Memorial Sloan-Kettering Cancer Center, 160 East 53rd Street, 2nd Floor, New York, NY, 10022, U.S.A.



Naevogenesis is a process known to occur throughout life. To date, investigators have made conclusions about new naevi in adults based on results of cross-sectional studies.


To determine the incidence of new naevus development in adults and to describe the dermoscopic morphology of new naevi.


A cohort of 182 patients seen at the outpatient dermatology clinic at Memorial Sloan-Kettering Cancer Center between 2000 and 2009 was evaluated with baseline total body photographs. The patients were aged 17 years or older and had presented for routine follow-up surveillance examination at least 3 months after baseline total body photographs. The number of new naevi and the dermoscopic morphology of these naevi were recorded.


Of the 182 patients evaluated, 50 (27%) developed at least one new naevus during follow-up. The incidence of new naevi was 202 per 1000 person-years of follow-up. The most common types of naevi were reticular (47·1%), followed by the homogeneous (22·1%) and complex (reticuloglobular) patterns (15·4%).


Our results provide support for the theory that there are two distinct pathways of naevogenesis, a dynamic process occurring throughout life. This study demonstrates that the predominant dermoscopic morphology of newly acquired naevi in adults is reticular.

[Indexed for MEDLINE]

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