Format

Send to

Choose Destination
See comment in PubMed Commons below
Tob Control. 2014 Nov;23(6):513-7. doi: 10.1136/tobaccocontrol-2012-050955. Epub 2013 Jun 21.

Heavy metal hazards of Nigerian smokeless tobacco.

Author information

1
Toxicology Unit, Faculty of Pharmacy, University of Port Hacourt, Port Harcourt, Rivers State, Nigeria.
2
Faculty of Pharmacy, Madonna University Elele, Rivers State, Nigeria.
3
Department of Medical Laboratory Science, Faculty of Science, Rivers State University of Science and Technology Port Hacourt, Port Hacourt, Rivers State, Nigeria.

Abstract

BACKGROUND:

Interest is rising in smokeless tobacco as a safer alternative to smoking. Information on the heavy metal hazards of smokeless tobacco is sparse in Nigeria, as it is in most sub-Saharan Africa countries. This study assesses the heavy metal hazards of the smokeless tobacco types commonly available in Nigeria.

METHODS:

Using a market basket protocol 30 Nigerian smokeless tobacco types were studied. Digestion was performed by addition of 10 mL of a mix of nitric and hydrochloric acids (HCl:HNO3, 3:1); the mixture was then heated to dryness. Then, 20 mL deionised water was added, and the mixture stirred and filtered. The filtrate was made up in a standard volumetric flask and lead, cadmium, chromium, cobalt and nickel concentrations were assayed with atomic absorption spectrophotometry at 205 Å. The daily intake and target hazard quotient (THQ) were calculated.

RESULTS:

Chromium, cobalt and nickel concentrations ranged from 2.77-11.40, 0.01-0.03 and 0.02-0.07 μg/g, respectively, whereas lead and cadmium ranged from 0.00-2.48 and 0.01-0.17 μg/g, respectively. The daily intake of chromium, cobalt and nickel ranged from 277-1140, 1-3 and 2 to 7 μg/day, respectively. Lead and cadmium daily intakes ranged from 0-248 and 1-17 μg/day, respectively.

CONCLUSIONS:

Although there was no apparent risk when each metal was analysed and considered individually, the potential risk could be multiplied when considering all heavy metals. The high heavy metal content in Nigerian smokeless tobacco may have public health implications.

KEYWORDS:

Environment; Global health; Primary Health Care; Toxicology

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center