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Cell Metab. 2013 Aug 6;18(2):153-61. doi: 10.1016/j.cmet.2013.05.017. Epub 2013 Jun 20.

Cellular fatty acid metabolism and cancer.

Author information

1
Department of Biochemistry & Biophysics, University of California, San Francisco, 94158, USA.

Abstract

Cancer cells often have characteristic changes in metabolism. Cellular proliferation, a common feature of all cancers, requires fatty acids for synthesis of membranes and signaling molecules. Here, we provide a view of cancer cell metabolism from a lipid perspective, and we summarize evidence that limiting fatty acid availability can control cancer cell proliferation.

PMID:
23791484
PMCID:
PMC3742569
DOI:
10.1016/j.cmet.2013.05.017
[Indexed for MEDLINE]
Free PMC Article

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