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Cell. 2013 Jun 20;153(7):1423-4. doi: 10.1016/j.cell.2013.05.054.

Inside-out connections: the ER meets the plasma membrane.

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  • 1Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Abstract

Junctions that connect the endoplasmic reticulum (ER) and the plasma membrane (PM) are unique yet ubiquitous subcellular compartments. Giordano et al. now report that extended synaptotagmins (E-Syts) promote their formation, providing fundamental insight into the molecular machinery controlling ER and plasma membrane crosstalk.

PMID:
23791170
DOI:
10.1016/j.cell.2013.05.054
[PubMed - indexed for MEDLINE]
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