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J Clin Exp Neuropsychol. 2013;35(7):669-76. doi: 10.1080/13803395.2013.809701. Epub 2013 Jun 21.

Odor identification and cognitive function in the Beaver Dam Offspring Study.

Author information

1
a Department of Ophthalmology and Visual Sciences , University of Wisconsin School of Medicine and Public Health , Madison , WI , USA.

Abstract

Olfactory impairment is associated with cognitive impairment in older adults but less is known about the association of olfactory impairment and cognitive function in middle-aged adults. The association between olfactory impairment and cognitive function tests of attention, processing speed, and executive and psychomotor function was explored in 2837 participants (21-84 years; mean age 49 years) in the Beaver Dam Offspring Study. Among middle-aged participants (aged 35-64 years), those with impairment on an odor identification test took significantly longer to complete the Trail Making Test (TMT-A and TMT-B) and the Grooved Peg Board (GPB) test, than those without olfactory impairment in regression models adjusted for multiple factors. Similar results were found for the TMT-A and TMT-B, but not the GPB, in the whole cohort. Olfactory impairment was associated with poorer performance on cognitive function tests in a primarily middle-aged cohort.

PMID:
23789858
PMCID:
PMC3778079
DOI:
10.1080/13803395.2013.809701
[Indexed for MEDLINE]
Free PMC Article

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