Format

Send to

Choose Destination
See comment in PubMed Commons below
Pan Afr Med J. 2013 Apr 9;14:141. doi: 10.11604/pamj.2013.14.141.2016. Print 2013.

Cardiovascular disease in children in Djibouti: a single-centre study.

Author information

1
Hôpital Laveran, 13 384 Marseille cedex 13, France.

Abstract

INTRODUCTION:

Few data are available about pediatric cardiovascular disease (CVD) in the Horn of Africa. The objective of this study was to describe the spectrum of CVD in children in Djibouti.

METHODS:

Clinical features and management of Djiboutian children between 1 month-old and 15 year-old with CVD were prospectively recorded over a two-year period in Bouffard Military Hospital in Djibouti (January 2009- December 2010).

RESULTS:

Clinical examination and echocardiography were performed on 156 patients: 32 of them (20%) had CVD. Three (10%) of them had Down's syndrome. The median age was 5 years (male 53%). Congenital heart disease was observed in 27 (84%) patients and dilated cardiomyopathy (DCM) in 5 (16%) patients including 2 patients with rheumatic valvular disease. Ventricular septal defect was frequent (28%). Other abnormalities were atrial septal defect (13%), Tetralogy of Fallot (9%), pulmonary stenosis (6%) and 3 other patients had multiple congenital anomalies condition. Surgical management was required in 22 (69%) patients and was performed on 15 (47%) cases. During follow up (mean 11.3 ± 6.8 months), 5 (16%) patients died. Absence of surgery was associated with significant mortality (p > 0.05) but age, sex and mean follow up were not.

CONCLUSION:

Pediatric CVD is at least as common in this Djiboutian community as in other African cohorts. The absence of surgery was a major mortality risk factor. DCM was frequent in this study. Much work remains to be done to discover the size and nature of genetic and environmental contributions to these various forms of heart diseases in the Horn of Africa.

KEYWORDS:

Congenital heart disease; Horn of Africa; cardiac surgery; dilated cardiomyopathy

PMID:
23785546
PMCID:
PMC3683514
DOI:
10.11604/pamj.2013.14.141.2016
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Pan African Medical Journal Icon for PubMed Central
    Loading ...
    Support Center