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J Chemother. 2013 Jun;25(3):148-55. doi: 10.1179/1973947813Y.0000000071.

Diagnosis of acute tonsillopharyngitis in primary care: a new approach for low-resource settings.

Author information

1
University of Uludag, Faculty of Medicine, Bursa, Turkey. zalper@uludag.edu.tr

Abstract

BACKGROUND:

Diagnosing GABHS (Group A-beta Hemolytic Streptococcus) tonsillopharyngitis by clinical scoring is a recommended approach in developed countries, but there is still much controversy for low resource settings.

AIM:

We aimed to assess the impact of Centor criteria with the support of practical laboratory tests.

METHODS:

We prospectively included patients complaining sore throat (N = 282). We evaluated them in terms of Centor scoring and performed white blood cell count (WBC), C-reactive protein (CRP), rapid antigen detecting test, and throat culture.

RESULTS:

In GABHS cases (N = 32, 11·3%), two of the criteria were observed to be positive in more than half of the cases (N = 19, 59·3%), while 13 (40·7%) cases met three/four criteria. The specificity of having two criteria was found to be 65·5% and increased to 91·5% after including CRP and WBC.

CONCLUSION:

Centor criteria could be safely used to reduce unnecessary antibiotic usage for tonsillopharyngitis in developing countries.

PMID:
23783139
DOI:
10.1179/1973947813Y.0000000071
[Indexed for MEDLINE]
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