Format

Send to

Choose Destination
See comment in PubMed Commons below
Expert Rev Mol Diagn. 2013 Jun;13(5):421-3. doi: 10.1586/erm.13.28.

Standards in molecular diagnostics for the discovery and validation of clinically useful cancer biomarkers.

Author information

1
Division of Cancer Prevention, National Cancer Institute, 9609 Medical Center Drive, Rockville, MD 20850, USA. vydelinn@mail.nih.gov

Abstract

Recent discoveries in cancer biology have greatly increased the understanding of cancer at the molecular level, but translating this knowledge into clinically useful diagnostic tests has proved challenging. More efficient transfer of new molecular tests into patient care requires better standardization of laboratory practices, measurement methods and data management. The workshop assembled experts from National Cancer Institute, US FDA, National Institute of Standards and Technology, academia and industry, to address the most efficient approaches to biomarker standardization and validation. The workshop participants described the current state of research in molecular diagnostics standardization and addressed three questions: what has worked? What has not?And what needs improving?

PMID:
23782249
DOI:
10.1586/erm.13.28
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center