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J Trop Pediatr. 2013 Dec;59(6):509-11. doi: 10.1093/tropej/fmt052. Epub 2013 Jun 18.

Intractable diarrhoea caused by cytomegalovirus enterocolitis in an immunocompetent term neonate.

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1
Department of Pediatrics, PGIMER & Dr RML Hospital, New Delhi 110001, India.

Abstract

Symptomatic cytomegalovirus (CMV) infection mainly affects preterm and immunocompromised infants and usually manifest as rash, pneumonia, hepatospleenomegaly or encephalitis. To our knowledge intractable diarrhoea at two weeks of age caused by postnatally acquired CMV in immunocompetent term neonate is not reported. An unusual case of postnatally acquired CMV enterocolitis manifesting as protracted diarrhoea in an immunocompetent baby in neonatal period is reported. We conclude that CMV should be considered in the differential diagnosis of intractable diarrhoea in neonatal period and treatment with intravenous ganciclovir for CMV enterocolitis is not only indicated but is therapeutic.

KEYWORDS:

cytomegalovirus; diarrhoea; ganciclovir; neonate

PMID:
23780993
DOI:
10.1093/tropej/fmt052
[Indexed for MEDLINE]
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