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Dev Cell. 2013 Jun 10;25(5):436-8. doi: 10.1016/j.devcel.2013.05.019.

My brain told me to do it.

Author information

1
Department of Neurobiology, David Geffen School of Medicine at UCLA, 610 Charles Young Drive East, Los Angeles, CA 90095, USA.

Abstract

Voluntary motor control requires circuits in the brain to develop synchronously with spinal motor circuitry. In this issue of Developmental Cell,Reimer et al. (2013) demonstrate that this process is coordinated in zebrafish: dopamine released from descending projections modulates formation of motor neurons by attenuating the response of progenitors to Shh signaling.

PMID:
23763945
DOI:
10.1016/j.devcel.2013.05.019
[Indexed for MEDLINE]
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