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Biomed Res Int. 2013;2013:742671. doi: 10.1155/2013/742671. Epub 2013 May 16.

An entropy-based model for basal ganglia dysfunctions in movement disorders.

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1
Department of Neurology, University of South Alabama, 307 University Boulevard, Mobile, AL 36608, USA. odarbin@usouthal.edu

Abstract

During this last decade, nonlinear analyses have been used to characterize the irregularity that exists in the neuronal data stream of the basal ganglia. In comparison to linear parameters for disparity (i.e., rate, standard deviation, and oscillatory activities), nonlinear analyses focus on complex patterns that are composed of groups of interspike intervals with matching lengths but not necessarily contiguous in the data stream. In light of recent animal and clinical studies, we present a review and commentary on the basal ganglia neuronal entropy in the context of movement disorders.

PMID:
23762856
PMCID:
PMC3671275
DOI:
10.1155/2013/742671
[Indexed for MEDLINE]
Free PMC Article
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