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Nutrients. 2013 May 29;5(6):1962-9. doi: 10.3390/nu5061962.

Macular pigment and its contribution to vision.

Author information

  • 1Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland. kate@ivr.ie

Abstract

Three dietary carotenoids, lutein (L), zeaxanthin (Z) and meso-zeaxanthin (MZ) accumulate at the central retina (macula), where they are collectively referred to as macular pigment (MP). MP's pre-receptoral absorption of blue light and consequential attenuation of the effects of chromatic aberration and light scatter are important for optimal visual function. Furthermore, antioxidant activity of MP's constituent carotenoids and the same blue light-filtering properties underlie the rationale for its putative protective role for age-related macular degeneration (AMD). Supplementation with L, Z and MZ augments MP and enhances visual performance in diseased and non-diseased eyes, and may reduce risk of AMD development and/or progression.

PMID:
23760061
PMCID:
PMC3725486
DOI:
10.3390/nu5061962
[PubMed - indexed for MEDLINE]
Free PMC Article
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