Format

Send to

Choose Destination
See comment in PubMed Commons below
Adv Anat Pathol. 2013 Jul;20(4):205-16. doi: 10.1097/PAP.0b013e3182976ed5.

Ductal carcinoma in situ: morphology-based knowledge and molecular advances.

Author information

1
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

Abstract

Ductal carcinoma in situ (DCIS) is an established precursor of invasive breast carcinoma. Immunoperoxidase stains for selected markers can assist pathologists in the diagnosis of challenging ductal epithelial proliferations, but they cannot replace morphologic evaluation as the primary and critical assessment of this disease. Molecular studies provide further insight into how DCIS progresses to invasive carcinoma and also confirm the heterogeneity of this lesion. Morphology-based knowledge, immunohistochemistry, and molecular advances in DCIS are the subjects of this review.

PMID:
23752083
DOI:
10.1097/PAP.0b013e3182976ed5
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wolters Kluwer
    Loading ...
    Support Center