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J Microbiol Immunol Infect. 2016 Feb;49(1):138-41. doi: 10.1016/j.jmii.2013.04.008. Epub 2013 Jun 14.

Tigecycline salvage therapy for necrotizing fasciitis caused by Vibrio vulnificus: Case report in a child.

Author information

1
Division of Plastic Surgery, Department of Surgery, Chi-Mei Medical Center, Tainan, Taiwan.
2
Institute of Biotechnology, National Cheng Kung University, Tainan, Taiwan; Medical Research, Chi Mei Medical Center, Tainan, Taiwan.
3
Department of Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan.
4
Department of Medicine, Chi Mei Medical Center, Tainan, Taiwan; Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan. Electronic address: ashiang68@gmail.com.

Abstract

Necrotizing fasciitis caused by Vibrio vulnificus is rarely reported in children. We describe a 12-year-old immunocompetent boy with necrotizing fasciitis caused by V. vulnificus. He was cured by radical and serial debridement and salvage therapy with intravenous cefpirome plus tigecycline. The in vitro antibacterial activity of combination regimens and a literature review of pediatric V. vulnificus infection are described.

KEYWORDS:

Child; Necrotizing fasciitis; Tigecycline; Vibrio vulnificus

PMID:
23751766
DOI:
10.1016/j.jmii.2013.04.008
[Indexed for MEDLINE]
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