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Nano Lett. 2013 Jul 10;13(7):3434-8. doi: 10.1021/nl402004s. Epub 2013 Jun 10.

Dynamic guiding of motor-driven microtubules on electrically heated, smart polymer tracks.

Author information

1
Max Planck Institute of Molecular Cell Biology and Genetics , 01307 Dresden, Germany.

Abstract

Biomolecular motor systems are attractive for future nanotechnological devices because they can replace nanofluidics by directed transport. However, the lack of methods to externally control motor-driven transport along complex paths limits their range of applications. Based on a thermo-responsive polymer, we developed a novel technique to guide microtubules propelled by kinesin-1 motors on a planar surface. Using electrically heated gold microstructures, the polymers were locally collapsed, creating dynamically switchable tracks that successfully guided microtubule movement.

PMID:
23750886
DOI:
10.1021/nl402004s
[Indexed for MEDLINE]

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