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Front Biosci (Landmark Ed). 2013 Jun 1;18:1237-43.

BNP and NT-proBNP levels in patients with sepsis.

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  • 1The First Hospital Affiliated to Dalian Medical University, Emergency Department, Dalian, Liaoning, 116011 China.


Sepsis is a severe complication of critically ill patients that is characterized by the systemic inflammatory response syndrome (SIRS). The increased levels of B-type natriuretic peptide (BNP) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) are related with dysfunction of the cardiovascular system and systemic inflammation. In recent years, BNP and NT-proBNP have been the focus of studies evaluating the severity and prognosis of sepsis. In this study, we will review the role of BNP and NT-proBNP in sepsis.

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