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Oncogene. 1990 Jul;5(7):1095-7.

Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6.

Author information

1
Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia 19104.

Abstract

We report here the full length cDNA sequence and the deduced amino-acid sequence of MyD88, a novel myeloid differentiation primary response gene activated in M1D+ myeloid precursors, following induction of terminal differentiation and growth arrest by IL6. Detectable levels of MyD88 RNA were observed in myeloid precursor enriched murine bone-marrow, but not in several other non-myeloid murine tissues.

PMID:
2374694
[Indexed for MEDLINE]

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