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Curr Biol. 2013 Jun 3;23(11):R481-3. doi: 10.1016/j.cub.2013.04.060.

Neuropeptide signaling: from the gut.

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1
MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.

Abstract

In the defecation motor program of Caenorhabditis elegans, a pacemaker rhythm generated by the intestine leads to the activation of motor neurons controlling enteric muscle contraction. A new study demonstrates that this signal is conveyed by a neuropeptide that is released from intestinal cells and acutely depolarizes the motorneurons, acting much like a classical neurotransmitter.

PMID:
23743414
DOI:
10.1016/j.cub.2013.04.060
[Indexed for MEDLINE]
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