Methyl carnosate, an antibacterial diterpene isolated from Salvia officinalis leaves

Nat Prod Commun. 2013 Apr;8(4):429-30.

Abstract

Ethanolic extracts of Salvia officinalis leaves demonstrated antibacterial activity against Bacillus cereus. Fractionation of the extracts led to the isolation of the most active antibacterial compound, which, from spectroscopic and LC-MS evidence, was proved to be the diterpene, methyl carnosate.

MeSH terms

  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Diterpenes / isolation & purification*
  • Diterpenes / pharmacology
  • Plant Extracts / analysis
  • Plant Extracts / pharmacology
  • Plant Leaves / chemistry
  • Salvia officinalis / chemistry*

Substances

  • Anti-Bacterial Agents
  • Diterpenes
  • Plant Extracts
  • methyl carnosate