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Muscles Ligaments Tendons J. 2012 Apr 1;1(4):169-71. Print 2011 Oct.

Tendon, tendon healing, hyperlipidemia and statins.

Author information

1
Department of Orthopedics and Traumatology; Goztepe research and Training Hospital, Kadıkoy, Istanbul, Turkey.

Abstract

Both hyperlipidemia and metabolic syndrome have adverse effect on tendon structure. Atorvastatin is most widely used antihyperlipidemic drug. Statins have adverse effects on the tendon. Many studies have analyzed the relationship between atorvastatin and skeletal muscles. Atorvastatin administered after the surgical repair of a ruptured tendon appears to affect revascularization, collagenization, inflammatory cell infiltration, and collagen construction. Therefore, further investigations on the effects of atorvastatin on tendon healing are needed.

KEYWORDS:

hyperlipidemia; statins; tendon; tendon healing

PMID:
23738266
PMCID:
PMC3666488

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