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Emerg Infect Dis. 2013 Jun;19(6):899-908. doi: 10.3201/eid1906.120543.

Zoonotic Mycobacterium bovis-induced tuberculosis in humans.

Author information

1
Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa. borna.mueller@gmail.com

Abstract

We aimed to estimate the global occurrence of zoonotic tuberculosis (TB) caused by Mycobacterium bovis or M. caprae infections in humans by performing a multilingual, systematic review and analysis of relevant scientific literature of the last 2 decades. Although information from many parts of the world was not available, data from 61 countries suggested a low global disease incidence. In regions outside Africa included in this study, overall median proportions of zoonotic TB of ≤1.4% in connection with overall TB incidence rates ≤71/100,000 population/year suggested low incidence rates. For countries of Africa included in the study, we multiplied the observed median proportion of zoonotic TB cases of 2.8% with the continental average overall TB incidence rate of 264/100,000 population/year, which resulted in a crude estimate of 7 zoonotic TB cases/100,000 population/year. These generally low incidence rates notwithstanding, available data indicated substantial consequences of this disease for some population groups and settings.

KEYWORDS:

Mycobacterium bovis; TB; bacteria; bovine tuberculosis; neglected tropical diseases; systematic review; tuberculosis and other mycobateria; zoonosis; zoonotic TB

PMID:
23735540
PMCID:
PMC4816377
DOI:
10.3201/eid1906.120543
[Indexed for MEDLINE]
Free PMC Article

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