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Pediatrics. 2013 Jul;132(1):161-5. doi: 10.1542/peds.2012-3643. Epub 2013 Jun 3.

Trisomy 18 and complex congenital heart disease: seeking the threshold benefit.

Author information

1
Department of Pediatrics, Johns Hopkins University School of Medicine, Johns Hopkins University School of Nursing, Baltimore, MD, USA. rboss1@jhmi.edu

Abstract

A prenatal diagnosis of ductal-dependent, complex congenital heart disease was made in a fetus with trisomy 18. The parents requested that the genetic diagnosis be excluded from all medical and surgical decision-making and that all life-prolonging therapies be made available to their infant. There was conflict among the medical team about what threshold of neonatal benefit could outweigh maternal and neonatal treatment burdens. A prenatal ethics consultation was requested.

KEYWORDS:

cardiac surgery; decision-making; ethics; trisomy 18

PMID:
23733790
DOI:
10.1542/peds.2012-3643
[Indexed for MEDLINE]

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