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J Microbiol Methods. 2013 Aug;94(2):133-134. doi: 10.1016/j.mimet.2013.05.015. Epub 2013 May 31.

Evaluation of a new chemiluminescence immunoassay for laboratory diagnosis of syphilis.

Author information

1
Microbiology Service, Virgen de las Nieves University Hospital, 18014 Granada, Spain.
2
Granada Sanitary District Northeast, 18500 Guadix, Granada, Spain.
3
Microbiology Service, Virgen de las Nieves University Hospital, 18014 Granada, Spain. Electronic address: javierm.rodriguez.sspa@juntadeandalucia.es.

Abstract

The purpose of this study was to evaluate diagnostic performances of automated chemiluminescence immunoassay (CLIA) in comparison with Treponema pallidum hemagglutination test (TPHA). The specificity of CLIA was 98.9% and 99.6% for TPHA, whereas the sensitivity was 98% and 96%, respectively. Considering the suitability for automation, CLIA may represent a suitable alternative.

KEYWORDS:

Antibody; Chemiluminescence; Syphilis; TPHA

PMID:
23732753
DOI:
10.1016/j.mimet.2013.05.015
[Indexed for MEDLINE]

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