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Korean J Ophthalmol. 2013 Jun;27(3):158-61. doi: 10.3341/kjo.2013.27.3.158. Epub 2013 Mar 19.

Evaluation of plasma vitamin A and E levels and tear film changes in patients with psoriasis vulgaris.

Author information

1
Department of Ophthalmology, Gaziosmanpasa University School of Medicine, Tokat, Turkey. helindeniz@hotmail.com

Abstract

PURPOSE:

To evaluate whether alterations in plasma vitamin A and E levels in patients with psoriasis have an effect on tear film changes.

METHODS:

Sixty-two eyes of 31 patients with psoriasis vulgaris (Group A) and 74 eyes of 37 age- and gender-matched control subjects (Group B) were included in the study. Ocular and medical histories and dietary habits were obtained from each patient. The tear film break-up time (TBUT), the Schirmer 1 test results and plasma vitamin A and E levels were evaluated.

RESULTS:

The mean Schirmer 1 test score was 14.76 ± 6.12 mm/5 min in Group A and 15.69 ± 3.10 mm/5 min in Group B. The mean plasma levels of vitamins A and E in Groups A and B were 1.86 ± 0.62 µmol/L and 1.88 ± 0.65 µmol/L vs. 26.21 ± 5.13 µmol/L and 27.19 ± 8.89 µmol/L, respectively. The Schirmer 1 test results and plasma vitamin A and E levels were not found to be significantly different between the groups (p > 0.05). The mean TBUT was 9.94 ± 6.18 seconds in Group A and 14.47 ± 5.65 seconds in Group B, a significant difference (p < 0.05). No correlation existed between plasma vitamin A and E levels, TBUT or the severity and duration of the disease (p > 0.05).

CONCLUSIONS:

Plasma vitamin A and E levels do not seem to be related to tear film changes in patients with psoriasis vulgaris.

KEYWORDS:

Ophthalmological diagnostic techniques; Psoriasis; Vitamin A; Vitamin E

PMID:
23730106
PMCID:
PMC3663056
DOI:
10.3341/kjo.2013.27.3.158
[Indexed for MEDLINE]
Free PMC Article

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