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Cell Rep. 2013 May 30;3(5):1335-6. doi: 10.1016/j.celrep.2013.05.011.

Tumor suppression by p53: is apoptosis important or not?

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1
Howard Hughes Medical Institute and Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO 80309, USA.

Abstract

The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Reports, Timofeev et al. (2013) and Valente et al. (2013) reveal context-dependent contributions of p53-dependent apoptosis to its tumor-suppressive function.

PMID:
23726020
DOI:
10.1016/j.celrep.2013.05.011
[Indexed for MEDLINE]
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