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Nat Methods. 2013 Jun;10(6):524-39. doi: 10.1038/nmeth.2482.

Imaging human connectomes at the macroscale.

Author information

1
Center for the Developing Brain, Child Mind Institute, New York, New York, USA.

Abstract

At macroscopic scales, the human connectome comprises anatomically distinct brain areas, the structural pathways connecting them and their functional interactions. Annotation of phenotypic associations with variation in the connectome and cataloging of neurophenotypes promise to transform our understanding of the human brain. In this Review, we provide a survey of magnetic resonance imaging–based measurements of functional and structural connectivity. We highlight emerging areas of development and inquiry and emphasize the importance of integrating structural and functional perspectives on brain architecture.

PMID:
23722212
PMCID:
PMC4096321
DOI:
10.1038/nmeth.2482
[Indexed for MEDLINE]
Free PMC Article

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