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Med Oral Patol Oral Cir Bucal. 2013 Jul 1;18(4):e619-26.

Malignant lymphoma of the oral cavity and the maxillofacial region: overall survival prognostic factors.

Author information

1
Faculty of Dentistry of the University de San Martín de Porres, USMP, Lima, Peru. janetguevara7@hotmail.com

Abstract

OBJECTIVE:

To identify the overall survival and prognostic factors of malignant lymphoma of the oral cavity and the maxillofacial region.

STUDY DESIGN:

Clinical records data were obtained in order to determine overall survival at 2 and 5 years, the individual survival percentage of each possible prognostic factor with the actuarial technique, and the survival regarding the possible prognostic factors with the actuarial technique and the Log-rank and Cox's regression tests.

RESULTS:

Of 151 subjects, an overall survival was 60% at 2 years, and 45% at 5 years. The multivariate analysis demonstrated statistically significant differences for clinical stage (p=0.002), extranodal involvement (p=0.030), presence of human immunodeficiency virus (p=0.032), and presence of Epstein-Barr virus (p=0.010).

CONCLUSION:

The advanced clinical stage and the larger number of involved extranodular sites are related to a lower overall survival, as well as, the presence of previous infections such as the human immunodeficiency and the Epstein-Barr virus.

PMID:
23722134
PMCID:
PMC3731090
[Indexed for MEDLINE]
Free PMC Article
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